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KMID : 1134820080370040459
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Journal of the Korean Society of Food Science and Nutrition
2008 Volume.37 No. 4 p.459 ~ p.464
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Effects of Milk with Boiled-Dried Large Anchovy, Calcium-Fortifying Materials and Fortified-Calcium Milk on Calcium Absorption Rate and Bone Metabolism in Rats
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Jo Jin-Ho
Kim Byung-G
Han Chan-Kyu
Jung Eun-Bong
Cho Seung-Mock
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Abstract
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This study was performed to investigate the effect of calcium-rich large anchovy on calcium metabolism
in rats for 5 weeks. Experimental animals were randomly assigned to 5 treatments with 14 heads of Spraque
Dawley male rats in each group. The experimental diets were as follows; market milk group (M) as control,
market milk＋calcium-rich large anchovy group (MA), market milk＋calcium carbonate group (MC), market
milk＋calcium lactate group (ML), and enriched-calcium market milk group (M2), which were formulated with
commercially semi-purified rat chow (AIN-diet) to maintain the same level of calcium (1%) in all groups.
Femur lengths of M and M2 groups were significantly higher than other groups. Bone mineral density (BMD)
and bone mineral content (BMC) and calcium content of femur were the highest in MA group than other groups.
In vitro and in vivo calcium absorption rates were high in MA group (7.30% vs 27.50%) compared with those
of the other groups. Serum total-cholesterol and HDL-cholesterol levels were significantly different between
M group and MA group (p<0.05). Creatinine levels were significantly higher in M, MA and MC groups than
in M2 group (p<0.05). Serum calcium, osteocalcin and ALPase activities were higher in calcium-rich large
anchovy (MA) group among the treatments, but there was no significant difference. SGOT activity was
significantly lower in M2 group than those of M, MA and MC groups (p<0.05). These results may indicate
that the calcium-rich large anchovy has enforced the BMD, BMC and calcium absorption rates of in vitro
and in vivo compared with the other groups and might be a calcium-enriched food with large anchovy.
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KEYWORD
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anchovy, calcium-carbonate, calcium-lactate, calcium absorption rate, bone metabolism, rats
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